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A collection of nonclinical studies & assays; customization is possible.

Cytoxicity assays for ISO/ICCVAM/HC: Balb/c C3T3; L929; MRC5

Study

Toxicology, In Vitro Alternate

The Balb/c c3T3, L929, and MRC5 cell lines are available for testing basal cytotoxicity with various protocols and a range of test substances. Study designs can be tailored to meet the specific data requirement needed.

Early in vitro toxicology assays can reliably characterize the safety profile of the test substance, thus reducing the number of animals required for in vivo studies. 

Assays vary according to the type of test substance or data requirement e.g., UNI EN ISO 10993/2009 guidance on MTS assays for exposure of L929 cells to a medical device test substance.

Industry Market

Chemical, Crop

Phase

Nonclinical

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About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC. Learn more about our commitment to replacing, reusing and refining nonclinical research models.

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Labcorp is a leading global life sciences company that includes contract research and developmental services to the pharmaceutical, medical technology, crop protection and chemical industries.

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