We provide a complete range of assays to determine the potential genetic toxicity of your novel drug, chemical or cosmetic. Our scientists have done this long before guidelines even existed. We conduct hundreds of assays to meet regulatory guidelines and GLP standards each year. Here are the most common.
Toxicology Services & Tests |
Hazard Identification (in vitro) |
Hazard Evaluation & Risk Assessment (in vivo) |
---|---|---|
Ames test |
* |
|
Gene mutation |
* |
|
Chromosomal aberration |
* |
|
Micronucleus |
** |
*** |
Comet |
* |
**** |
Combined micronucleus/Comet |
|
*** / **** |
Non-disjunction testing using FISH or antikinetochore |
* |
|
Cytotoxicity & phototoxicity |
* |
|
Clinical trial & occupational cytogenetics monitoring |
* |
|
EPISKIN™ |
* |
|
EpiDerm™ |
* |
|
Eye irritation (BCOP) |
* |
|
Rodent bone marrow cytogenetics |
|
* |
Transgenic rodent mutation assays (Muta™Mouse) |
|
**** |
30% MORE GENETIC TOXICOLOGY SPACE
Leading the way with new study options rooted in the 3Rs
The world’s demand for safe products is growing, and the demand for innovation in genetic toxicology and in vitro models is growing along with it. This is why we have expanded our genetic toxicology facilities by 30 percent, including new in vitro alternatives. Explore all of your genetic toxicology study options.
MAKING YOUR BREAKTHROUGHS POSSIBLE
Our major commitment to your Early Development studies
Over the past five years, we’ve invested more than $700 million in nonclinical development to enhance our capabilities for your programs. From expanded lab space in our U.S., European and Asia Pacific sites to state-of-the-art instrumentation and digitized workflows, we’ve innovated where it matters most to empower your healthcare mission.
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