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Vaccine Development Testing

Access a comprehensive suite of discovery vaccine testing services, enabling the development of human and veterinary vaccines against viral and bacterial pathogens. With more than four decades of experience working with a variety of vaccine types within a full range of in vivo and in vitro services, we can be an ideal partner for all your vaccine development needs.

Vaccine development and solution-based discovery

We work with all common vaccine types: subunit, live/attenuated, inactivated and toxoid

In vitro capabilities
- Humoral immune response analysis: Analyze various antibody response types in the well-equipped laboratories using ELISA, neutralization assays, HAI and other tests
- Cell-mediated immune response: Decipher Th1 and Th2 responses by ELISpot in a dedicated tissue culture facility
In vivo capabilities
- Immunogenicity studies: Select from a variety of host species ranging from rodents to nonhuman primates with rapid study starts and scalability from a few to a large number of animals
- Efficacy/challenge: Evaluate your vaccine’s efficacy in our vivariums supporting up to BSL2 pathogens in custom-developed or standard research models

Immunogenicity Studies

Immunogenicity studies are a combination of in vivo and in vitro services providing you with a complete evaluation of the immunogenicity of your test vaccines. We work with you as part of a comprehensive development plan to identify a suitable host species (based on the nature of the vaccine) and to recommend sample analysis methods.

Anthrax
Bordella bronchiseptica
Dengue Virus
Malaria
Plague - Yersinia pestis
Hepatitis A
Hepatitis B
Human Papilloma Virus
HIV – AIDS
Influenza
Staphylocccous aureus
Ricin
Human Rota Virus
Respiratory syncytial virus (RSV)

Efficacy/Challenge Studies

Following satisfactory immunogenicity results, efficacy or challenge studies can be conducted using a standard or custom animal model. Pathogens up to BSL2 can be tested in our state-of-the-art vivariums in studies ranging in size from small pilot studies to larger, complex designs. Samples originating from these in vivo studies can be transferred to our laboratories for further analysis.

C. difficile
Human papillomavirus (HPV)
Influenza
Methicillin-resistant Staphylococcus aureus (MRSA)
Rabies
Respiratory syncytial virus (RSV)

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ENHANCING VACCINES AND ANTIBODY RESEARCH

Lab expansions to match your growing needs

Equipped with state-of-the-art technology, our new sample analysis lab space in Denver, Pa., provides one-stop service for in vivo testing and in vitro analysis so you can receive faster results for your vaccine and antibody research and development.

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See how all of us at Labcorp are supporting treatments and vaccines for the COVID-19 pandemic

“I want to extend my sincere thanks to you for your performance demonstrated during the challenge phase of our preclinical vaccine study. By all accounts the quality and workmanship of the service provided has been exceptional. The efforts of your management team to work expeditiously, intelligently and honestly has been key for successful execution of this challenging experiment. It has truly been a pleasure to work with you and we look forward to continuing this practice in the future.”

– Large Pharma Client

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Vaccine Development Testing

Vaccine development and solution-based discovery

Immunogenicity Studies

Efficacy/Challenge Studies

Lab expansions to match your growing needs

See how all of us at Labcorp are supporting treatments and vaccines for the COVID-19 pandemic

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