Toxicity studies: Subchronic

Study

Toxicology, Subchronic (0-26 wk)

Subchronic Toxicity Studies are used to determine crucial parameters for chronic toxicity studies, which include, but are not limited to the following:

Establish adverse effects, not detected in short-term studies
Identify the observed effect of dose levels and NOAEL (no-observed-adverse-effect-level)
Provide data for dose selection for chronic toxicity
Identify the target organ/site of action
Provide data extrapolation for regulatory agencies
Forecast a risk assessment

Subchronic Toxicology Studies are typically ordered for 28-day or 90-day timeframes; but other options are possible.

Molecule or Product Type

Biologics, Small Molecule

Models

Canine, Mini-pig, Mouse, NHP, Rabbit, Rat

Administration Routes

Dermal, Dietary, Gavage, Infusion, Intramuscular, Intrathecal, Intravenous, Ocular, Subcutaneous

Regulatory

IND & CTA

Industry Market

Pharma

Phase

Nonclinical

Request a Quote

About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC. Learn more about our commitment to replacing, reusing and refining nonclinical research models.