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A collection of nonclinical studies & assays; customization is possible.

Radiosynthesis assessments

Technique

Metabolism, Metabolite Identification, Environmental

Radiosynthesis assessments are chemical tests that evaluate metabolism, degradation and final fate in animals, humans or the environment. 

One or more atoms of the test substance are replaced by a radioisotope, for example 14C, producing multiple radiolabeled substances that are used to track the biotransformation of the test substance. 

For example, 

  • Radiolabeled peptides have been studied for positron emission tomography (PET) tumor imaging potential in mice bearing A549 tumors. 
  • Tracers for the serotonin 7 (5‐HT7) receptor have also been assessed within the CNS therapy field.

Molecule or Product Type

Cell & Gene Therapies, Small Molecule

Industry Market

Chemical, Crop, Pharma

Phase

Discovery, Nonclinical

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About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC. Learn more about our commitment to replacing, reusing and refining nonclinical research models.

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Labcorp is a leading global life sciences company that includes contract research and developmental services to the pharmaceutical, medical technology, crop protection and chemical industries.

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