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Microautoradiography techniques
Microautoradiography, or MARG, is a high-resolution imaging technique used to qualitatively resolve the localization of radiolabeled compounds at the cellular level in a histological preparation from an animal model.
MARG provides a qualitative assessment of the relative distribution of drug-related radioactivity at the subcellular level.
The technique allows the direct visualization of the stained tissue with the co-localization of the radioactivity, which through nuclear emulsion staining allows radioactivity to be visualized as silver grains.
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