Electro-ejaculation techniques
Electro-ejaculation techniques for NHP studies use electrical stimuli to collect semen samples. A key factor of the procedure is ensuring NHPs are well-trained as they are not anesthetized, thus decreasing urine contamination and increasing the numbers of sperm per ejaculation. Depending on the species, timing and dilution of semen cryoprotectants need to be considered.
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OECD 426: Developmental neurotoxicity study
DART, Neurotoxicity -
Ovarian follicle counting (for ovarian toxicity)
Pathology, DART, Anatomic Pathology -
Sperm assessment testing for in-life or post-mortem
Anatomic Pathology, DART -
Cesarean section
Toxicology, Pathology, Anatomic Pathology, DART -
ePPND and EFD NHP studies
DART